NOT ALL BRAND NAME BIOLOGICS AND BIOSIMILARS WORK
IN THE SAME WAY

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    The “mechanism of action” of a
    brand name biologic or biosimilar is
    what the drug does inside the body
    to treat a disease – in other words,
    how it works1

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    There are multiple “classes” of brand name biologics and biosimilars for chronic immunological diseases (e.g., plaque psoriasis, Crohn’s disease, ulcerative colitis, and rheumatoid arthritis)2

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    Each class is categorized by what
    the biologic treatments target within
    the body2

Some of the targets that brand name biologics and/or biosimilars may interact with include:3

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    Tumour necrosis
    factor alpha
    (TNFα)

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    B cells
    (Anti-CD20)

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    T cells
    (T cell activation inhibitors/
    co-stimulation modulators)

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    Interleukins
    (IL-6, IL-12/23, IL-17,
    and IL-23)

Not all brand-name biologics have a corresponding biosimilar